Current position:Product Center > Pseudovirus > SARS-CoV-2 pseudovirus
SARS-CoV-2 pseudovirus
简介

S蛋白是冠状病毒最重要的表面膜蛋白,含有S1和S2两个亚基。其中S1包含受体结合域(receptorbinding domain, RBD),负责识别细胞的受体。S2含有膜融合过程所需的基本元件。研究发现,S蛋白介导受体结合和膜融合,对病毒感染宿主细胞起重要作用,此外,S蛋白上含有刺激中和抗体的主要抗原及细胞毒性淋巴细胞的重要靶标,是疫苗设计、治疗性抗体和诊断方法的关键靶标(Walls et al., 2020; Wang et al., 2020; Zhang et al., 2020)。


为避免传统的SARS-CoV-2病毒中和试验需要操作活毒而存在的生物安全隐患,吉满生物建立了基于假病毒系统的操作较安全的SARS-CoV-2中和试验技术平台。本产品以HIV慢病毒载体和SARS-CoV-2 S蛋白为基础,将SARS-CoV-2 S蛋白替换慢病毒包膜蛋白VSVG,与慢病毒包装质粒和CMV-GFP-T2A-Luciferase质粒共转染293T细胞,包装SARS-CoV-2 S假病毒,表面表达SARS-CoV-2 S蛋白,并且同时携带GFP荧光和Luciferase荧光素酶报告基因,可通过观察荧光和检测荧光素酶活性评价假病毒感染细胞的活性,该假病毒无自主复制能力,安全性高,可用于SARS-CoV-2受体药物筛选、中和抗体检测及疫苗效果评价等


新冠假病毒现货清单
产品货号 产品名称
GM-0220PV07
SARS-CoV-2 Spike Pseudotyped Virus (GFP-Luciferase)
GM-0220PV10
SARS-CoV-2 Spike(R408I) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV11
SARS-CoV-2 Spike(N354D) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV12
SARS-CoV-2 Spike(V367F) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV14
SARS-CoV-2 Spike(D614G) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV15
SARS-CoV-2 Spike(D614G+I472V) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV16
SARS-CoV-2 Spike(D839Y) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV16
SARS-CoV-2 Spike(V483A) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV18
SARS-CoV-2 Spike(D614G+L5F) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV19
SARS-CoV-2 Spike(D614G+D936Y) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV20
SARS-CoV-2 Spike(L5F) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV21
SARS-CoV-2 Spike(L8V) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV22
SARS-CoV-2 Spike(L8W) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV24
SARS-CoV-2 Spike(D614G+A831V) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV25
SARS-CoV-2 Spike(D614G+A879S) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV28
SARS-CoV-2 Spike(N501Y) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV29
SARS-CoV-2 Spike(N501Y+D614G) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV30
SARS-CoV-2 Spike(K417N) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV31
SARS-CoV-2 Spike(K417N+E484K+N501Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV32
SARS-CoV-2 Spike(B.1.351/501Y.V2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV33
SARS-CoV-2 Spike(B.1.1.7/VUI-202012/01,del145Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV34
SARS-CoV-2 Spike(B.1.1.7/VUI-202012/01,del144Y/145Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV35
SARS-CoV-2 Spike(E484K)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV36
SARS-CoV-2 Spike(E484K+N501Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV37
SARS-COV-2 Spike(B.1.429 CAL.20C)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV38
SARS-COV-2 Spike(K417T+E484K+N501Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV39
SARS-COV-2 Spike(B1.1.298/Y453F)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV40
SARS-COV-2 Spike(B.1.258,B.1.141/B1.258/N439K)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV42
SARS-COV-2 Spike(L452R+E484Q)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV43
SARS-COV-2 Spike(B.1.617)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV44
SARS-COV-2 Spike(B.1.617.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV45
SARS-COV-2 Spike(B.1.617.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV46
SARS-COV-2 Spike(B.1.617.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV47
SARS-COV-2 Spike(P.1 501Y.V3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV48
SARS-COV-2 Spike(B.1.525)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV49
SARS-COV-2 Spike(P.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV50
SARS-COV-2 Spike(B.1.427+B.1.429)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV51
SARS-COV-2 Spike(Delta+)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV52
SARS-COV-2 Spike(Lambda;del247-253)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV53
SARS-COV-2 Spike(Lambda)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV83
SARS-COV-2 Spike(B.1.621)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV84
SARS-COV-2 Spike(B.1.1.529)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV85
SARS-COV-2 Spike(B.1.640.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV86
SARS-COV-2 Spike(BA.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV87
SARS-COV-2 Spike(BA.1.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV88
SARS-COV-2 Spike(BA.2.9)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV90
SARS-COV-2 Spike(BA.5)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV92
SARS-COV-2 Spike(BA.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV93
SARS-COV-2 spike(BA.2.12.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV94
SARS-COV-2 S-Protein(Q493R) Pseudotype Virus(GFP-T2A-Luciferase)
GM-0220PV97
SARS-COV-2 S-Protein(L452Q) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV98
SARS-COV-2 Spike(BA.4)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV99
SARS-COV-2 Spike(BA.2.75)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV100
SARS-COV-2 Spike(BF.7)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV101
SARS-COV-2 Spike(BA.2.76)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV102
SARS-COV-2 Spike(XBB)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV103
SARS-COV-2 Spike(BQ.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV104
SARS-COV-2 Spike(XBB.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV105
SARS-COV-2 Spike(BQ.1.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV106
SARS-COV-2 Spike(XBB.1.5)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV107
SARS-COV-2 Spike(BN.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV108
SARS-COV-2 Spike(CH.1.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV109
SARS-COV-2 Spike(BA.2.3.20)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV110
SARS-COV-2 Spike(XBC)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV111
SARS-COV-2 Spike(XAY)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV112
SARS-COV-2 Spike(BF.7.14)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV113
SARS-COV-2 Spike(XBB.1.9.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV114
SARS-COV-2 Spike(XBB.1.9)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV115
SARS-COV-2 Spike(XBB.2.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV116
SARS-COV-2 Spike(XBB.1.6)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV117
SARS-COV-2 Spike(XBB.1.5.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV118
SARS-COV-2 Spike(BN.1.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV119
SARS-COV-2 Spike(BN.1.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV120
SARS-COV-2 Spike(XBB.1.16)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV121
SARS-COV-2 Spike(XBB.1.9.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV122
SARS-COV-2 Spike(EG.5)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV135
SARS-COV-2 Spike(XBB.1.16.6)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV137
SARS-COV-2 Spike(BA.2.86)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV138
SARS-CoV-2 Spike(EG.5.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV139
SARS-CoV-2 Spike(FL.1.5.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV140
SARS-COV-2 Spike(EG.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV144
SARS-COV-2 Spike(HV.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV145
SARS-COV-2 Spike(HF.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV146
SARS-CoV-2 spike(JN.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV147
SARS-CoV-2 spike(HK.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV149
SARS-COV-2 Spike(XBB.1.22) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV150
SARS-COV-2 Spike(BA.2.86.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV151
SARS-COV-2 Spike(BA.2.86.2) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV152
SARS-COV-2 Spike(BA.2.86.3) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV153
SARS-COV-2 Spike(JQ.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV154
SARS-COV-2 Spike(JN.2) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV155
SARS-COV-2 Spike(JN.3) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV156
SARS-COV-2 Spike(JN.1.4) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV157
SARS-COV-2 Spike(JN.1.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV163
SARS-COV-2 Spike(JN.1.13) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV165
SARS-COV-2 Spike(KP.2) Pseudotyped Virus (GFP-Luciferase)
GM-C12968
H_ACE2 HEK-293T Cell Line
Product Center > Pseudovirus > SARS-CoV-2 pseudovirus
classify
SARS-CoV-2 pseudovirus
新冠假病毒现货清单
产品货号 产品名称
GM-0220PV07
SARS-CoV-2 Spike Pseudotyped Virus (GFP-Luciferase)
GM-0220PV10
SARS-CoV-2 Spike(R408I) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV11
SARS-CoV-2 Spike(N354D) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV12
SARS-CoV-2 Spike(V367F) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV14
SARS-CoV-2 Spike(D614G) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV15
SARS-CoV-2 Spike(D614G+I472V) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV16
SARS-CoV-2 Spike(D839Y) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV16
SARS-CoV-2 Spike(V483A) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV18
SARS-CoV-2 Spike(D614G+L5F) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV19
SARS-CoV-2 Spike(D614G+D936Y) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV20
SARS-CoV-2 Spike(L5F) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV21
SARS-CoV-2 Spike(L8V) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV22
SARS-CoV-2 Spike(L8W) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV24
SARS-CoV-2 Spike(D614G+A831V) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV25
SARS-CoV-2 Spike(D614G+A879S) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV28
SARS-CoV-2 Spike(N501Y) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV29
SARS-CoV-2 Spike(N501Y+D614G) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV30
SARS-CoV-2 Spike(K417N) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV31
SARS-CoV-2 Spike(K417N+E484K+N501Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV32
SARS-CoV-2 Spike(B.1.351/501Y.V2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV33
SARS-CoV-2 Spike(B.1.1.7/VUI-202012/01,del145Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV34
SARS-CoV-2 Spike(B.1.1.7/VUI-202012/01,del144Y/145Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV35
SARS-CoV-2 Spike(E484K)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV36
SARS-CoV-2 Spike(E484K+N501Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV37
SARS-COV-2 Spike(B.1.429 CAL.20C)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV38
SARS-COV-2 Spike(K417T+E484K+N501Y)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV39
SARS-COV-2 Spike(B1.1.298/Y453F)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV40
SARS-COV-2 Spike(B.1.258,B.1.141/B1.258/N439K)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV42
SARS-COV-2 Spike(L452R+E484Q)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV43
SARS-COV-2 Spike(B.1.617)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV44
SARS-COV-2 Spike(B.1.617.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV45
SARS-COV-2 Spike(B.1.617.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV46
SARS-COV-2 Spike(B.1.617.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV47
SARS-COV-2 Spike(P.1 501Y.V3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV48
SARS-COV-2 Spike(B.1.525)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV49
SARS-COV-2 Spike(P.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV50
SARS-COV-2 Spike(B.1.427+B.1.429)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV51
SARS-COV-2 Spike(Delta+)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV52
SARS-COV-2 Spike(Lambda;del247-253)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV53
SARS-COV-2 Spike(Lambda)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV83
SARS-COV-2 Spike(B.1.621)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV84
SARS-COV-2 Spike(B.1.1.529)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV85
SARS-COV-2 Spike(B.1.640.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV86
SARS-COV-2 Spike(BA.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV87
SARS-COV-2 Spike(BA.1.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV88
SARS-COV-2 Spike(BA.2.9)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV90
SARS-COV-2 Spike(BA.5)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV92
SARS-COV-2 Spike(BA.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV93
SARS-COV-2 spike(BA.2.12.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV94
SARS-COV-2 S-Protein(Q493R) Pseudotype Virus(GFP-T2A-Luciferase)
GM-0220PV97
SARS-COV-2 S-Protein(L452Q) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV98
SARS-COV-2 Spike(BA.4)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV99
SARS-COV-2 Spike(BA.2.75)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV100
SARS-COV-2 Spike(BF.7)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV101
SARS-COV-2 Spike(BA.2.76)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV102
SARS-COV-2 Spike(XBB)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV103
SARS-COV-2 Spike(BQ.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV104
SARS-COV-2 Spike(XBB.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV105
SARS-COV-2 Spike(BQ.1.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV106
SARS-COV-2 Spike(XBB.1.5)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV107
SARS-COV-2 Spike(BN.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV108
SARS-COV-2 Spike(CH.1.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV109
SARS-COV-2 Spike(BA.2.3.20)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV110
SARS-COV-2 Spike(XBC)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV111
SARS-COV-2 Spike(XAY)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV112
SARS-COV-2 Spike(BF.7.14)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV113
SARS-COV-2 Spike(XBB.1.9.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV114
SARS-COV-2 Spike(XBB.1.9)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV115
SARS-COV-2 Spike(XBB.2.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV116
SARS-COV-2 Spike(XBB.1.6)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV117
SARS-COV-2 Spike(XBB.1.5.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV118
SARS-COV-2 Spike(BN.1.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV119
SARS-COV-2 Spike(BN.1.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV120
SARS-COV-2 Spike(XBB.1.16)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV121
SARS-COV-2 Spike(XBB.1.9.2)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV122
SARS-COV-2 Spike(EG.5)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV135
SARS-COV-2 Spike(XBB.1.16.6)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV137
SARS-COV-2 Spike(BA.2.86)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV138
SARS-CoV-2 Spike(EG.5.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV139
SARS-CoV-2 Spike(FL.1.5.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV140
SARS-COV-2 Spike(EG.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV144
SARS-COV-2 Spike(HV.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV145
SARS-COV-2 Spike(HF.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV146
SARS-CoV-2 spike(JN.1)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV147
SARS-CoV-2 spike(HK.3)Pseudotyped Virus (GFP-Luciferase)
GM-0220PV149
SARS-COV-2 Spike(XBB.1.22) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV150
SARS-COV-2 Spike(BA.2.86.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV151
SARS-COV-2 Spike(BA.2.86.2) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV152
SARS-COV-2 Spike(BA.2.86.3) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV153
SARS-COV-2 Spike(JQ.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV154
SARS-COV-2 Spike(JN.2) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV155
SARS-COV-2 Spike(JN.3) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV156
SARS-COV-2 Spike(JN.1.4) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV157
SARS-COV-2 Spike(JN.1.1) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV163
SARS-COV-2 Spike(JN.1.13) Pseudotyped Virus (GFP-Luciferase)
GM-0220PV165
SARS-COV-2 Spike(KP.2) Pseudotyped Virus (GFP-Luciferase)
GM-C12968
H_ACE2 HEK-293T Cell Line
简介

S蛋白是冠状病毒最重要的表面膜蛋白,含有S1和S2两个亚基。其中S1包含受体结合域(receptorbinding domain, RBD),负责识别细胞的受体。S2含有膜融合过程所需的基本元件。研究发现,S蛋白介导受体结合和膜融合,对病毒感染宿主细胞起重要作用,此外,S蛋白上含有刺激中和抗体的主要抗原及细胞毒性淋巴细胞的重要靶标,是疫苗设计、治疗性抗体和诊断方法的关键靶标(Walls et al., 2020; Wang et al., 2020; Zhang et al., 2020)。


为避免传统的SARS-CoV-2病毒中和试验需要操作活毒而存在的生物安全隐患,吉满生物建立了基于假病毒系统的操作较安全的SARS-CoV-2中和试验技术平台。本产品以HIV慢病毒载体和SARS-CoV-2 S蛋白为基础,将SARS-CoV-2 S蛋白替换慢病毒包膜蛋白VSVG,与慢病毒包装质粒和CMV-GFP-T2A-Luciferase质粒共转染293T细胞,包装SARS-CoV-2 S假病毒,表面表达SARS-CoV-2 S蛋白,并且同时携带GFP荧光和Luciferase荧光素酶报告基因,可通过观察荧光和检测荧光素酶活性评价假病毒感染细胞的活性,该假病毒无自主复制能力,安全性高,可用于SARS-CoV-2受体药物筛选、中和抗体检测及疫苗效果评价等


Catologe
SARS-CoV-2 Spike Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(R408I) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(N354D) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(V367F) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(D614G) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(D614G+I472V) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(D839Y) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 S-Protein(Q493R) Pseudotype Virus(GFP-Luciferase) SARS-COV-2 S-Protein(L452Q) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.4)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.2.75)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BF.7)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.2.76)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BQ.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BQ.1.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1.5)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BN.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(CH.1.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(EG.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.2.3.20)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBC)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XAY)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(HV.1)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 spike(JN.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BF.7.14)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(V483A) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1.9.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1.22) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1.9)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(D614G+L5F) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.2.3)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(D614G+D936Y) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.2.86.1) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1.6)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(L5F) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1.5.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.2.86.2) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BN.1.2)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BN.1.3)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.2.86.3) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1.16)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(L8V) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1.9.2)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(JQ.1) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(L8W) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(EG.5)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(JN.2) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(D614G+A831V) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(XBB.1.16.6)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(JN.3) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(JN.1.4) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(JN.1.1) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(D614G+A879S) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(JN.1.13) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(KP.2) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(N501Y) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(N501Y+D614G) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(K417N) Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.2.86)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(K417N+E484K+N501Y)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(EG.5.1) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(B.1.351/501Y.V2)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(FL.1.5.1) Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(B.1.1.7/VUI-202012/01,del145Y)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(B.1.1.7/VUI-202012/01,del144Y/145Y)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(E484K)Pseudotyped Virus (GFP-Luciferase) SARS-CoV-2 Spike(E484K+N501Y)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.429 CAL.20C)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(K417T+E484K+N501Y)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B1.1.298/Y453F)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.258,B.1.141/B1.258/N439K)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(L452R+E484Q)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 spike(BA.2.12.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.3)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.617)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.617.1)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.617.2)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.617.3)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(P.1 501Y.V3)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.525)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(P.2)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.427+B.1.429)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(Delta+)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(Lambda;del247-253)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(Lambda)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.621)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.1.529)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(B.1.640.2)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.2)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.2.9)Pseudotyped Virus (GFP-Luciferase) SARS-COV-2 Spike(BA.5)Pseudotyped Virus (GFP-Luciferase) H_ACE2 HEK-293T Cell Line
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