Cat. No：GM-87691AB
Product：Anti-BAFFR hlgG1 Antibody(ianalumab)
Cat. No：GM-87691AB
Product：Anti-BAFFR hlgG1 Antibody(ianalumab)
GM-87691AB-10 10 μg
GM-87691AB-100 100 μg
GM-87691AB-1000 1 mg
Species Reactivity Human
Clone ianalumab
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry
Specificity Detects BAFFR
Gene BAFFR
Other Names BAFF-R, TNFRSF13C, BROMIX, CD268, CVID4, prolixin
Gene ID 115650 (human)
Background B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-87691AB
Product：Anti-BAFFR hlgG1 Antibody(ianalumab)
GM-87691AB-10 10 μg
GM-87691AB-100 100 μg
GM-87691AB-1000 1 mg
Species Reactivity Human
Clone ianalumab
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry
Specificity Detects BAFFR
Gene BAFFR
Other Names BAFF-R, TNFRSF13C, BROMIX, CD268, CVID4, prolixin
Gene ID 115650 (human)
Background B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
