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Current position:Product Center > Antibodies > Biosimilar Antibodies > Anti-CLDN18.2 hIgG1 Antibody(Zolbetuximab)
Anti-CLDN18.2 hIgG1 Antibody(Zolbetuximab)
Product Info

Cat. No:GM-34137AB

Product :Anti-CLDN18.2 hIgG1 Antibody(Zolbetuximab)



Cat. No. & Size

GM-34137A-10           10 μg

GM-34137A-100         100 μg

GM-34137A-1000       1mg


Description

Species Reactivity      Human; Cynomolgus

Clone                           Zolbetuximab

Source/Isotype           Monoclonal Human IgG1 /κ

Application                 Flow Cytometry

Specificity                   Detects CLDN18.2

Gene                            CLDN18.2

Other Names              /

Gene ID                       51208(Human); 9541 (Cynomolgus)

Background                The claudin18.2 (CLDN18.2) protein, an isoform of claudin18, a member of the tight junction protein family, is a highly selective biomarker with limited expression in normal tissues and often abnormal expression during the occurrence and development of various primary malignant tumors, such as gastric cancer/gastroesophageal junction (GC/GEJ) cancer, breast cancer, colon cancer, liver cancer, head and neck cancer, bronchial cancer and non-small-cell lung cancer. CLDN18.2 participates in the proliferation, differentiation and migration of tumor cells. Recent studies have identified CLDN18.2 expression as a potential specific marker for the diagnosis and treatment of these tumors. With its specific expression pattern, CLDN18.2 has become a unique molecule for targeted therapy in different cancers, especially in GC; for example, agents such as zolbetuximab (claudiximab, IMAB362), a monoclonal antibody (mAb) against CLDN18.2, have been developed.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


Data

/ueditor/image/20240516/1715844795428408/e4360429e64b1ecb50100d2757c06eb2.png

/ueditor/image/20240516/1715844799912736/ffa0a45e73b55592145308522e51e1c7.png


Current position:Product Center > -- > Anti-CLDN18.2 hIgG1 Antibody(Zolbetuximab)
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Anti-CLDN18.2 hIgG1 Antibody(Zolbetuximab)
Product Info

Cat. No:GM-34137AB

Product :Anti-CLDN18.2 hIgG1 Antibody(Zolbetuximab)



Cat. No. & Size

GM-34137A-10           10 μg

GM-34137A-100         100 μg

GM-34137A-1000       1mg


Description

Species Reactivity      Human; Cynomolgus

Clone                           Zolbetuximab

Source/Isotype           Monoclonal Human IgG1 /κ

Application                 Flow Cytometry

Specificity                   Detects CLDN18.2

Gene                            CLDN18.2

Other Names              /

Gene ID                       51208(Human); 9541 (Cynomolgus)

Background                The claudin18.2 (CLDN18.2) protein, an isoform of claudin18, a member of the tight junction protein family, is a highly selective biomarker with limited expression in normal tissues and often abnormal expression during the occurrence and development of various primary malignant tumors, such as gastric cancer/gastroesophageal junction (GC/GEJ) cancer, breast cancer, colon cancer, liver cancer, head and neck cancer, bronchial cancer and non-small-cell lung cancer. CLDN18.2 participates in the proliferation, differentiation and migration of tumor cells. Recent studies have identified CLDN18.2 expression as a potential specific marker for the diagnosis and treatment of these tumors. With its specific expression pattern, CLDN18.2 has become a unique molecule for targeted therapy in different cancers, especially in GC; for example, agents such as zolbetuximab (claudiximab, IMAB362), a monoclonal antibody (mAb) against CLDN18.2, have been developed.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


Data

/ueditor/image/20240516/1715844795428408/e4360429e64b1ecb50100d2757c06eb2.png

/ueditor/image/20240516/1715844799912736/ffa0a45e73b55592145308522e51e1c7.png


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