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Current position:Product Center > Antibodies > Biosimilar Antibodies > Anti-H_FcRn IgG4 Antibody(Rozanolixizumab)
Anti-H_FcRn IgG4 Antibody(Rozanolixizumab)
Product info

Cat.No:GM-37413AB

Product:Anti-H_FcRn hIgG4 Antibody(Rozanolixizumab)



Cat. No. & Size

GM-37413AB-10       10 μg

GM-37413AB-100     100 μg

GM-37413AB-1000   1 mg

Description️

Species Reactivity       Human

Clone                           Rozanolixizumab

Source/Isotype           Monoclonal human IgG4, κ

Application                 Flow cytometry

Specificity                   Detects FcRn.

Gene                            FcRn

Other Names              FCGRT, FcgammaRn, alpha-chain

Gene ID                       2217(human)

Background                The neonatal Fc receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the FCGRT gene. It is an IgG Fc receptor which is similar in structure to the MHC class I molecule and also associates with beta-2-microglobulin. In rodents, FcRn was originally identified as the receptor that transports maternal immunoglobulin G (IgG) from mother to neonatal offspring via mother's milk, leading to its name as the neonatal Fc receptor. In humans, FcRn is present in the placenta where it transports mother's IgG to the growing fetus. FcRn has also been shown to play a role in regulating IgG and serum albumin turnover. Neonatal Fc receptor expression is up-regulated by the proinflammatory cytokine, TNF-α, and down-regulated by IFN-γ.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


Data

/ueditor/image/20240514/1715673196305019/88bd74438f3172fce708368f593dd6ef.png

Current position:Product Center > -- > Anti-H_FcRn IgG4 Antibody(Rozanolixizumab)
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Anti-H_FcRn IgG4 Antibody(Rozanolixizumab)
Product info

Cat.No:GM-37413AB

Product:Anti-H_FcRn hIgG4 Antibody(Rozanolixizumab)



Cat. No. & Size

GM-37413AB-10       10 μg

GM-37413AB-100     100 μg

GM-37413AB-1000   1 mg

Description️

Species Reactivity       Human

Clone                           Rozanolixizumab

Source/Isotype           Monoclonal human IgG4, κ

Application                 Flow cytometry

Specificity                   Detects FcRn.

Gene                            FcRn

Other Names              FCGRT, FcgammaRn, alpha-chain

Gene ID                       2217(human)

Background                The neonatal Fc receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the FCGRT gene. It is an IgG Fc receptor which is similar in structure to the MHC class I molecule and also associates with beta-2-microglobulin. In rodents, FcRn was originally identified as the receptor that transports maternal immunoglobulin G (IgG) from mother to neonatal offspring via mother's milk, leading to its name as the neonatal Fc receptor. In humans, FcRn is present in the placenta where it transports mother's IgG to the growing fetus. FcRn has also been shown to play a role in regulating IgG and serum albumin turnover. Neonatal Fc receptor expression is up-regulated by the proinflammatory cytokine, TNF-α, and down-regulated by IFN-γ.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


Data

/ueditor/image/20240514/1715673196305019/88bd74438f3172fce708368f593dd6ef.png

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