Cat. No：GM-32251AB
Product：Anti-H_PDCD1LG2 mIgG1 Antibody(3G2)
Cat. No：GM-32251AB
Product：Anti-H_PDCD1LG2 mIgG1 Antibody(3G2)
GM-32251AB-10 10 μg
GM-32251AB-100 100 μg
GM-32251AB-1000 1mg
Species Reactivity Human
Clone 3G2
Source/Isotype Mouse IgG1, κ
Application Flow Cytometry
Specificity Detects PDCD1LG2
Gene PDCD1LG2
Other Names PD-L2; Btdc; PDL2; bA574F11.2; CD273; B7-DC
Gene ID 80380
Background PD-L2 is a cell surface receptor belonging to the B7 protein family. It consists of both an immunoglobulin-like variable domain and an immunoglobulin-like constant domain in the extracellular region, a transmembrane domain, and a cytoplasmic domain. PD-L2 is primarily expressed on professional antigen presenting cells including dendritic cells (DCs) and macrophages. PD-L2 Binding to PD-1 can activate pathways inhibiting TCR/BCR-mediated immune cell activation. PD-L2 plays an important role in immune tolerance and autoimmunity. PD-L2 can inhibit T cell proliferation and inflammatory cytokine production. Blocking PD-L2 has been shown to exacerbate experimental autoimmune encephalomyelitis.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-32251AB
Product：Anti-H_PDCD1LG2 mIgG1 Antibody(3G2)
GM-32251AB-10 10 μg
GM-32251AB-100 100 μg
GM-32251AB-1000 1mg
Species Reactivity Human
Clone 3G2
Source/Isotype Mouse IgG1, κ
Application Flow Cytometry
Specificity Detects PDCD1LG2
Gene PDCD1LG2
Other Names PD-L2; Btdc; PDL2; bA574F11.2; CD273; B7-DC
Gene ID 80380
Background PD-L2 is a cell surface receptor belonging to the B7 protein family. It consists of both an immunoglobulin-like variable domain and an immunoglobulin-like constant domain in the extracellular region, a transmembrane domain, and a cytoplasmic domain. PD-L2 is primarily expressed on professional antigen presenting cells including dendritic cells (DCs) and macrophages. PD-L2 Binding to PD-1 can activate pathways inhibiting TCR/BCR-mediated immune cell activation. PD-L2 plays an important role in immune tolerance and autoimmunity. PD-L2 can inhibit T cell proliferation and inflammatory cytokine production. Blocking PD-L2 has been shown to exacerbate experimental autoimmune encephalomyelitis.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
