Cat.No：GM-86367MAB
Product ：Anti-H_ACVR2B hIgG1 Reference Antibody(Bimbio)
Cat.No：GM-86367MAB
Product ：Anti-H_ACVR2B hIgG1 Reference Antibody(Bimbio)
GM-86367MAB-1mg / 1 mg
GM-86367MAB-5mg / 5 mg
GM-86367MAB-25mg / 25 mg
GM-86367MAB-50mg / 50mg
GM-86367MAB-100mg / 100 mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target ACVR2B
Clone Bimagrumab
Alternative Names BYM338，ACVR2B (activin A receptor type 2B, ActR-IIB, ActRIIB)
Source/Isotype Monoclonal Human IgG1(REEM), Kappa
Application ELISA；Flow Cytometry
Description ACVR2B (Activin A receptor type IIB) is an important cell membrane receptor protein belonging to the TGF-β receptor family, playing a key role in regulating cell growth, proliferation, and differentiation processes. The function of ACVR2B is closely related to its interaction with other signaling proteins such as Activin and Myostatin. By regulating the phosphorylation level of Smad proteins and activating other signaling pathways, ACVR2B can influence the fate and function of cells.
Formulation Phosphate-buffered solution, pH 7.2.
Cat.No：GM-86367MAB
Product ：Anti-H_ACVR2B hIgG1 Reference Antibody(Bimbio)
GM-86367MAB-1mg / 1 mg
GM-86367MAB-5mg / 5 mg
GM-86367MAB-25mg / 25 mg
GM-86367MAB-50mg / 50mg
GM-86367MAB-100mg / 100 mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target ACVR2B
Clone Bimagrumab
Alternative Names BYM338，ACVR2B (activin A receptor type 2B, ActR-IIB, ActRIIB)
Source/Isotype Monoclonal Human IgG1(REEM), Kappa
Application ELISA；Flow Cytometry
Description ACVR2B (Activin A receptor type IIB) is an important cell membrane receptor protein belonging to the TGF-β receptor family, playing a key role in regulating cell growth, proliferation, and differentiation processes. The function of ACVR2B is closely related to its interaction with other signaling proteins such as Activin and Myostatin. By regulating the phosphorylation level of Smad proteins and activating other signaling pathways, ACVR2B can influence the fate and function of cells.
Formulation Phosphate-buffered solution, pH 7.2.
