Cat. No：GM-86675AB
Product：Anti-B7-H6 hIgG1 Antibody(h12F5)
Cat. No：GM-86675AB
Product：Anti-B7-H6 hIgG1 Antibody(h12F5)
GM-86675AB-10 10 μg
GM-86675AB-100 100 μg
GM-86675AB-1000 1 mg
Species Reactivity Human
Clone h12F5
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry
Specificity Detects B7-H6
Gene B7-H6
Other Names NCR3LG1 , B7H6, B7-H6, DKFZp686O24166
Gene ID Q68D85 (human); XP_005578557.1 (Cynomolgus)
Background B7-H6 is a type I transmembrane protein belonging to the B7 family, characterized by two immunoglobulin domains. It also serves as a ligand for the NK cell-activating receptor NKp30. While B7-H6 is prominently expressed on various tumor cells, no B7-H6 mRNA has been detected in normal human tissues or healthy peripheral blood mononuclear cells. In an inflammatory milieu, certain pro-inflammatory cytokines like IL‑1β and TNF can induce the upregulation of B7-H6 expression in CD14+CD16+ monocytes and neutrophils. The tumor expression spectrum of B7-H6 is extensive, encompassing leukemia, lymphoma, colorectal cancer, non-small cell lung cancer, breast cancer, ovarian cancer, stomach cancer, and liver cancer.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-86675AB
Product：Anti-B7-H6 hIgG1 Antibody(h12F5)
GM-86675AB-10 10 μg
GM-86675AB-100 100 μg
GM-86675AB-1000 1 mg
Species Reactivity Human
Clone h12F5
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry
Specificity Detects B7-H6
Gene B7-H6
Other Names NCR3LG1 , B7H6, B7-H6, DKFZp686O24166
Gene ID Q68D85 (human); XP_005578557.1 (Cynomolgus)
Background B7-H6 is a type I transmembrane protein belonging to the B7 family, characterized by two immunoglobulin domains. It also serves as a ligand for the NK cell-activating receptor NKp30. While B7-H6 is prominently expressed on various tumor cells, no B7-H6 mRNA has been detected in normal human tissues or healthy peripheral blood mononuclear cells. In an inflammatory milieu, certain pro-inflammatory cytokines like IL‑1β and TNF can induce the upregulation of B7-H6 expression in CD14+CD16+ monocytes and neutrophils. The tumor expression spectrum of B7-H6 is extensive, encompassing leukemia, lymphoma, colorectal cancer, non-small cell lung cancer, breast cancer, ovarian cancer, stomach cancer, and liver cancer.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
