Cat. No：GM-27130AB
Product：Anti-H_CAIX hIgG1 Antibody(girentuximab)
Cat. No：GM-27130AB
Product：Anti-H_CAIX hIgG1 Antibody(girentuximab)
GM-27130AB-10 10 μg
GM-27130AB-100 100 μg
GM-27130AB-1000 1mg
Species Reactivity Human
Specificity Detects human CAIX.
Source/Isotype Monoclonal Human IgG1/κ
Other Names CA9; MN
Gene ID 768
Application Flow cytometry: 1 μg-4 μg /1E6 cells; FC-Quality tested
Background Carbonic anhydrase IX (CA9/CA IX) is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase isoforms found in humans and is a transmembrane dimeric metalloenzyme with an extracellular active site that facilitates acid secretion in the gastrointestinal tract. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CA IX is overexpressed in many types of cancer including clear cell renal cell carcinoma (RCC) as well as carcinomas of the cervix, breast and lung where it promotes tumor growth by enhancing tumor acidosis.
Storage Store at +4℃ short term (1-2 weeks). Store at -20℃ long term
Formulation Phosphate-buffered solution, pH 7.2.
Cat. No：GM-27130AB
Product：Anti-H_CAIX hIgG1 Antibody(girentuximab)
GM-27130AB-10 10 μg
GM-27130AB-100 100 μg
GM-27130AB-1000 1mg
Species Reactivity Human
Specificity Detects human CAIX.
Source/Isotype Monoclonal Human IgG1/κ
Other Names CA9; MN
Gene ID 768
Application Flow cytometry: 1 μg-4 μg /1E6 cells; FC-Quality tested
Background Carbonic anhydrase IX (CA9/CA IX) is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase isoforms found in humans and is a transmembrane dimeric metalloenzyme with an extracellular active site that facilitates acid secretion in the gastrointestinal tract. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CA IX is overexpressed in many types of cancer including clear cell renal cell carcinoma (RCC) as well as carcinomas of the cervix, breast and lung where it promotes tumor growth by enhancing tumor acidosis.
Storage Store at +4℃ short term (1-2 weeks). Store at -20℃ long term
Formulation Phosphate-buffered solution, pH 7.2.
