Cat.No：GM-31294AB
Product：Anti-H_BDCA2 hIgG1 Antibody(Litifilimab)
Cat.No：GM-31294AB
Product：Anti-H_BDCA2 hIgG1 Antibody(Litifilimab)
GM-31294AB-10 10 μg
GM-31294AB-100 100 μg
GM-31294AB-1000 1 mg
Species Reactivity Human; Cynomolgus
Clone Litifilimab
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry; Activation assay
Specificity Detects BDCA2
Gene BDCA2
Other Names BDCA-2, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150, CLEC4C
Gene ID 170482(human); A0A2K5UWP4(Cynomolgus)
Background BDCA2 (Blood Dendritic Cell Antigen 2) is a cell surface antigen primarily expressed in a subset of dendritic cells. BDCA2 plays a crucial role in the immune system, particularly in regulating immune responses and antigen presentation processes. Research has shown that BDCA2 functions involve modulating the activity of dendritic cells and the activation status of T cells, thus impacting the expression of immune responses. Studying BDCA2 helps deepen our understanding of the functions and regulatory mechanisms of dendritic cells in the immune system, providing valuable insights for disease treatment and the development of immunotherapy.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-31294AB
Product：Anti-H_BDCA2 hIgG1 Antibody(Litifilimab)
GM-31294AB-10 10 μg
GM-31294AB-100 100 μg
GM-31294AB-1000 1 mg
Species Reactivity Human; Cynomolgus
Clone Litifilimab
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry; Activation assay
Specificity Detects BDCA2
Gene BDCA2
Other Names BDCA-2, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150, CLEC4C
Gene ID 170482(human); A0A2K5UWP4(Cynomolgus)
Background BDCA2 (Blood Dendritic Cell Antigen 2) is a cell surface antigen primarily expressed in a subset of dendritic cells. BDCA2 plays a crucial role in the immune system, particularly in regulating immune responses and antigen presentation processes. Research has shown that BDCA2 functions involve modulating the activity of dendritic cells and the activation status of T cells, thus impacting the expression of immune responses. Studying BDCA2 helps deepen our understanding of the functions and regulatory mechanisms of dendritic cells in the immune system, providing valuable insights for disease treatment and the development of immunotherapy.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
