Cat.No：GM-26561AB
Product ：Anti-H_TROP2 hIgG1 Antibody(datopotamab)
Cat.No：GM-26561AB
Product ：Anti-H_TROP2 hIgG1 Antibody(datopotamab)
GM-26561AB-10 10 μg
GM-26561AB-100 100 μg
GM-26561AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Datopotamab
Source/Isotype Monoclonal Human IgG1, κ
Application Flow Cytometry
Specificity Detects TROP2
Gene TROP2
Other Names EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TACSTD2
Gene ID 4070(human); 102127436(cynomolgus)
Background TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-26561AB
Product ：Anti-H_TROP2 hIgG1 Antibody(datopotamab)
GM-26561AB-10 10 μg
GM-26561AB-100 100 μg
GM-26561AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Datopotamab
Source/Isotype Monoclonal Human IgG1, κ
Application Flow Cytometry
Specificity Detects TROP2
Gene TROP2
Other Names EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TACSTD2
Gene ID 4070(human); 102127436(cynomolgus)
Background TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
