Cat.No：GM-23369AB
Product：Anti-H_Nectin4 hIgG1 Antibody (Enfortumab)
Cat.No：GM-23369AB
Product：Anti-H_Nectin4 hIgG1 Antibody (Enfortumab)
GM-23369AB-10 10 μg
GM-23369AB-100 100 μg
GM-23369AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Enfortumab
Source/Isotype Monoclonal Human IgG1, κ
Application Flow Cytometry
Specificity Detects Nectin4
Gene Nectin4
Other Names EDSS1, LNIR, PRR4, PVRL4, nectin-4
Gene ID 81607(human), 102127936(cynomolgus)
Background This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-23369AB
Product：Anti-H_Nectin4 hIgG1 Antibody (Enfortumab)
GM-23369AB-10 10 μg
GM-23369AB-100 100 μg
GM-23369AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Enfortumab
Source/Isotype Monoclonal Human IgG1, κ
Application Flow Cytometry
Specificity Detects Nectin4
Gene Nectin4
Other Names EDSS1, LNIR, PRR4, PVRL4, nectin-4
Gene ID 81607(human), 102127936(cynomolgus)
Background This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
