Cat.No：GM-23370AB
Product：Anti-H_CCR4 hIgG1 Antibody(Mogamulizumab)
Cat.No：GM-23370AB
Product：Anti-H_CCR4 hIgG1 Antibody(Mogamulizumab)
GM-23370AB-10 10 μg
GM-23370AB-100 100 μg
GM-23370AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Mogamulizumab
Source/Isotype Monoclonal human IgG1
Application Flow Cytometry
Specificity Detects CCR4
Gene CCR4
Other Names CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5
Gene ID P51679 (human); G7NYB7-1 (Cynomolgus)
Background CCR4 is a G protein-linked seven transmembrane domain chemokine receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. CCR4 is often expressed on leukemic cells in cutaneous T-cell lymphoma (CTCL).
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-23370AB
Product：Anti-H_CCR4 hIgG1 Antibody(Mogamulizumab)
GM-23370AB-10 10 μg
GM-23370AB-100 100 μg
GM-23370AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Mogamulizumab
Source/Isotype Monoclonal human IgG1
Application Flow Cytometry
Specificity Detects CCR4
Gene CCR4
Other Names CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5
Gene ID P51679 (human); G7NYB7-1 (Cynomolgus)
Background CCR4 is a G protein-linked seven transmembrane domain chemokine receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. CCR4 is often expressed on leukemic cells in cutaneous T-cell lymphoma (CTCL).
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
