Cat. No：GM-50886AB
Product：Anti-TNFRSF10B(DR5) hIgG1 Antibody(drozitumab)
Cat. No：GM-50886AB
Product：Anti-TNFRSF10B(DR5) hIgG1 Antibody(drozitumab)
GM-50886AB-10 10 μg
GM-50886AB-100 100 μg
GM-50886AB-1000 1mg
Species Reactivity Human
Clone drozitumab
Source/Isotype Monoclonal human IgG1, λ
Application Flow cytometry
Other Names CD85J, ILT-2, LIR-1, LIR1, MIR-7, MIR7, PIR-B, PIRB
Specificity Detects TNFRSF10B.
Gene TNFRSF10B(DR5)
Background The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L) and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-50886AB
Product：Anti-TNFRSF10B(DR5) hIgG1 Antibody(drozitumab)
GM-50886AB-10 10 μg
GM-50886AB-100 100 μg
GM-50886AB-1000 1mg
Species Reactivity Human
Clone drozitumab
Source/Isotype Monoclonal human IgG1, λ
Application Flow cytometry
Other Names CD85J, ILT-2, LIR-1, LIR1, MIR-7, MIR7, PIR-B, PIRB
Specificity Detects TNFRSF10B.
Gene TNFRSF10B(DR5)
Background The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L) and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
