Cat.No：GM-48031AB
Product：Anti-ROR1 hIgG1 Antibody(Zilovertamab/Cirmtuzumab)
Cat.No：GM-48031AB
Product：Anti-ROR1 hIgG1 Antibody(Zilovertamab/Cirmtuzumab)
GM-48031AB-10 10 μg
GM-48031AB-100 100 μg
GM-48031AB-1000 1mg
Species Reactivity Human; Cynomolgus; Mouse
Clone Zilovertamab/Cirmtuzumab
Source/Isotype Monoclonal human IgG1, κ
Application Flow Cytometry
Specificity Detects ROR1
Gene ROR1
Other Names NTRKR1, dJ537F10.1
Gene ID NM_005012.4 (Human); XM_015434778.1 (Cynomolgus) ; NM_013845.5 (Mouse)
Background This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-48031AB
Product：Anti-ROR1 hIgG1 Antibody(Zilovertamab/Cirmtuzumab)
GM-48031AB-10 10 μg
GM-48031AB-100 100 μg
GM-48031AB-1000 1mg
Species Reactivity Human; Cynomolgus; Mouse
Clone Zilovertamab/Cirmtuzumab
Source/Isotype Monoclonal human IgG1, κ
Application Flow Cytometry
Specificity Detects ROR1
Gene ROR1
Other Names NTRKR1, dJ537F10.1
Gene ID NM_005012.4 (Human); XM_015434778.1 (Cynomolgus) ; NM_013845.5 (Mouse)
Background This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
