Current position:Product Center > Antibodies > Biosimilar Antibodies > Anti-H_TNFRSF9(4-1BB) hIgG4 Antibody (Urelumab)
Anti-H_TNFRSF9(4-1BB) hIgG4 Antibody (Urelumab)
Product info

Cat.No:GM-28954AB

Product:Anti-H_TNFRSF9(4-1BB) hIgG4 Antibody (Urelumab)




Cat. No. & Size

GM-28954AB-10           10 μg

GM-28954AB-100         100 μg

GM-28954AB-1000       1mg

Description️

Species Reactivity      Human; Cynomolgus

Clone                           Urelumab

Source/Isotype           Monoclonal Human IgG4 /κ

Application                 Flow Cytometry; Activation assay

Specificity                   Detects 4-1BB

Gene                            TNFRSF9

Other Names              CD137, CDw137, ILA, IMD109

Gene ID                       3604

Background                4-1BB, as one representative TNF receptor family co-stimulatory receptor, is expressed on a wide variety of cell types, including activated T cells, NK cells, DCs, B cells,monocytes, and neutrophils. 4-1BBL–4-1BB interaction can trigger an activation signal in all these cell types. However, anti-4-1BB-induced CD8+ T responses were thought to play a dominant role in anti-tumor immunity. Anti-4-1BB agonistic Abs could induce more effector molecules released from CD8+ T cells, increase proliferation and decrease apoptosis of CD8+ T cells, which all count for the enhanced anti-tumor immunity.It specifically binds to and ctivates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells. 

Storage                       Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                   < 1 EU/mg, determined by LAL gel clotting assay

Data

/ueditor/image/20240524/1716539699856281/70ff52f7c3036882e959a5684b5ef3dc.png


/ueditor/image/20240524/1716539718892914/bf6164c011be285bbd5fa9d2efc270da.png

Relevant data
Current position:Product Center > -- > Anti-H_TNFRSF9(4-1BB) hIgG4 Antibody (Urelumab)
classify
Anti-H_TNFRSF9(4-1BB) hIgG4 Antibody (Urelumab)
Product info

Cat.No:GM-28954AB

Product:Anti-H_TNFRSF9(4-1BB) hIgG4 Antibody (Urelumab)




Cat. No. & Size

GM-28954AB-10           10 μg

GM-28954AB-100         100 μg

GM-28954AB-1000       1mg

Description️

Species Reactivity      Human; Cynomolgus

Clone                           Urelumab

Source/Isotype           Monoclonal Human IgG4 /κ

Application                 Flow Cytometry; Activation assay

Specificity                   Detects 4-1BB

Gene                            TNFRSF9

Other Names              CD137, CDw137, ILA, IMD109

Gene ID                       3604

Background                4-1BB, as one representative TNF receptor family co-stimulatory receptor, is expressed on a wide variety of cell types, including activated T cells, NK cells, DCs, B cells,monocytes, and neutrophils. 4-1BBL–4-1BB interaction can trigger an activation signal in all these cell types. However, anti-4-1BB-induced CD8+ T responses were thought to play a dominant role in anti-tumor immunity. Anti-4-1BB agonistic Abs could induce more effector molecules released from CD8+ T cells, increase proliferation and decrease apoptosis of CD8+ T cells, which all count for the enhanced anti-tumor immunity.It specifically binds to and ctivates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells. 

Storage                       Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                   < 1 EU/mg, determined by LAL gel clotting assay

Data

/ueditor/image/20240524/1716539699856281/70ff52f7c3036882e959a5684b5ef3dc.png


/ueditor/image/20240524/1716539718892914/bf6164c011be285bbd5fa9d2efc270da.png

Relevant data
Tel: 400-627-9288
Message consultation
reset
submit
Service
WhatApp
Phone
Message
Message consultation
reset
submit