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Current position:Product Center > Antibodies > Biosimilar Antibodies > Anti-CD19 hIgG1 Reference Antibody (Loncbio)
Anti-CD19 hIgG1 Reference Antibody (Loncbio)
Product Info

Cat.No:GM-87912MAB

Product:Anti-CD19 hIgG1 Reference Antibody (Loncbio)


Cat. No & Size

GM-87912MAB-1mg / 1 mg

GM-87912MAB-5mg / 5 mg

GM-87912MAB-25mg / 25 mg

GM-87912MAB-50mg / 50 mg

GM-87912MAB-100mg / 100mg




Description

Expression System      CHO

Aggregation                < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          CD19

Clone                         Loncastuximab

Alternative Names   B4, CVID3

Source/Isotype         Human IgG1 (D356E/L358M),Kappa

Application               /

Description               B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein that in humans is encoded by the gene CD19. In humans, CD19 is expressed in all B lineage cells. CD19 plays two major roles in human B cells: on the one hand, it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane; on the other, it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.

Formulation                phosphate-buffered solution, pH 7.4.

Data

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Current position:Product Center > -- > Anti-CD19 hIgG1 Reference Antibody (Loncbio)
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Anti-CD19 hIgG1 Reference Antibody (Loncbio)
Product Info

Cat.No:GM-87912MAB

Product:Anti-CD19 hIgG1 Reference Antibody (Loncbio)


Cat. No & Size

GM-87912MAB-1mg / 1 mg

GM-87912MAB-5mg / 5 mg

GM-87912MAB-25mg / 25 mg

GM-87912MAB-50mg / 50 mg

GM-87912MAB-100mg / 100mg




Description

Expression System      CHO

Aggregation                < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          CD19

Clone                         Loncastuximab

Alternative Names   B4, CVID3

Source/Isotype         Human IgG1 (D356E/L358M),Kappa

Application               /

Description               B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein that in humans is encoded by the gene CD19. In humans, CD19 is expressed in all B lineage cells. CD19 plays two major roles in human B cells: on the one hand, it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane; on the other, it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.

Formulation                phosphate-buffered solution, pH 7.4.

Data

image.png

image.png



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