Cat. No：GM-53193AB
Product：Anti-αvβ6 hIgG1 Antibody(m15H3)
Cat. No：GM-53193AB
Product：Anti-αvβ6 hIgG1 Antibody(m15H3)
GM-53193AB-10 10 μg
GM-53193AB-100 100 μg
GM-53193AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone m15H3
Source/Isotype Monoclonal Human IgG1/κ
Application Flow Cytometry
Specificity Detects αvβ6
Gene αVβ6
Other Names αVβ6; avb6; CD51/β6; ITGAV/ITGB6; Integrin alpha v beta 6
Gene ID ITGAV: 3685(human)、ITGAV: A0A2K5WCD3 (Cynomolgus)；TIGB6: 3694 (human)、TIGB6: A0A2K5TZ36 (Cynomolgus)
Background Integrins are heterodimeric transmembrane receptors comprising alpha and beta subunits that function as cell anchoring and signaling molecules. ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins which span the cell’s membrane, integrating the outside and inside of the cell. Integrins bind to specific extracellular proteins in the extracellular matrix or on other cells and subsequently transduce signals intracellularly to affect cell behaviour.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-53193AB
Product：Anti-αvβ6 hIgG1 Antibody(m15H3)
GM-53193AB-10 10 μg
GM-53193AB-100 100 μg
GM-53193AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone m15H3
Source/Isotype Monoclonal Human IgG1/κ
Application Flow Cytometry
Specificity Detects αvβ6
Gene αVβ6
Other Names αVβ6; avb6; CD51/β6; ITGAV/ITGB6; Integrin alpha v beta 6
Gene ID ITGAV: 3685(human)、ITGAV: A0A2K5WCD3 (Cynomolgus)；TIGB6: 3694 (human)、TIGB6: A0A2K5TZ36 (Cynomolgus)
Background Integrins are heterodimeric transmembrane receptors comprising alpha and beta subunits that function as cell anchoring and signaling molecules. ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins which span the cell’s membrane, integrating the outside and inside of the cell. Integrins bind to specific extracellular proteins in the extracellular matrix or on other cells and subsequently transduce signals intracellularly to affect cell behaviour.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
