MICA (MHC class I polypeptide-related sequence A) and MICB (MHC class I polypeptide-related sequence B) are two non-classical molecules within the major histocompatibility complex (MHC) class I family. They are stress-induced ligands that play a crucial role in immune responses. MICA and MICB are key molecules recognized by NK cells and T cells through the NKG2D receptor, and they are commonly associated with tumor cells, viral infections, and autoimmune diseases.
Genomeditech provides resources related to MICA and MICB targets, including expression cell lines, proteins, and antibodies, to support activity validation and in vitro efficacy evaluation of MICA and MICB-related drugs.
