C-MET (also known as MET or Hepatocyte Growth Factor Receptor, HGFR) is a receptor tyrosine kinase (RTK) whose ligand is HGF (Hepatocyte Growth Factor). The C-MET and HGF signaling axis plays a critical role in cell proliferation, migration, invasion, angiogenesis, and tissue repair. Abnormal activation of the C-MET: HGF signaling pathway is closely associated with the occurrence, progression, and metastasis of various cancers, making it an important focus in tumor-targeted therapy research.
Genomeditech provides a variety of research tools related to the C-MET target, including overexpression cell lines, functional cell lines, proteins, and antibodies. These resources comprehensively support the in vitro activity validation of related drugs, offering strong support for researchers in evaluating and optimizing drug development, and facilitating their application and translation in tumor immunotherapy.
