Cat. No：GM-51478AB
Product：Anti-CD3 epsilon Antibody [OKT-3 (muromonab)]
Cat. No：GM-51478AB
Product：Anti-CD3 epsilon Antibody [OKT-3 (muromonab)]
GM-51478AB-10 10 μg
GM-51478AB-100 100 μg
GM-51478AB-1000 1 mg
Species Reactivity Human
Clone muromonab
Source/Isotype Human IgG1, κ
Application Activation assay
Specificity Detects CD3E
Gene CD3E
Other Names CD3E; CD3 epsilon; T3E; TCRE;T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e; OKT3
Antibody Other Names Muromonab; Muromonab-CD3; Orthoclone-OKT3; Muromonab OKT-3
Background CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. The CD3 receptor is a membrane protein on the surface of T cells. Muromonab is an immunosuppressant drug given to reduce acute rejection in patients with organ transplants. It is a monoclonal antibody targeted at the CD3 receptor.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-51478AB
Product：Anti-CD3 epsilon Antibody [OKT-3 (muromonab)]
GM-51478AB-10 10 μg
GM-51478AB-100 100 μg
GM-51478AB-1000 1 mg
Species Reactivity Human
Clone muromonab
Source/Isotype Human IgG1, κ
Application Activation assay
Specificity Detects CD3E
Gene CD3E
Other Names CD3E; CD3 epsilon; T3E; TCRE;T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e; OKT3
Antibody Other Names Muromonab; Muromonab-CD3; Orthoclone-OKT3; Muromonab OKT-3
Background CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. The CD3 receptor is a membrane protein on the surface of T cells. Muromonab is an immunosuppressant drug given to reduce acute rejection in patients with organ transplants. It is a monoclonal antibody targeted at the CD3 receptor.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
