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Reporter gene detection-related reagents
Reporter Gene

A reporter gene is a type of gene that makes the expression product easy to detect. Its mechanism involves fusing the coding sequence of the reporter gene and its expression regulatory sequence with the target gene to form a chimeric gene. Under the influence of the regulatory sequence, the gene is expressed. By detecting the expression product of the reporter gene, the expression status of the target gene can be evaluated.


Common reporter genes include luciferase, chloramphenicol acetyltransferase (CAT), β-galactosidase (β-gal), secreted alkaline phosphatase (SEAP), and green fluorescent protein (GFP), among others.

Firefly Luciferase

Firefly luciferase is a protein with a molecular weight of approximately 61 kDa. Under conditions where ATP, magnesium ions, and oxygen are present, it catalyzes the oxidation of luciferin to oxyluciferin. During this oxidation process, it emits bioluminescence with a wavelength of around 560 nm.


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Due to its strong specificity, high sensitivity, low endogenous activity, and resistance to interference from other substances within the cell, luciferase is widely used as a reporter gene (marker protein).



Product Application

It is suitable for bioactivity detection based on reporter genes, such as Fc effector assays, T cell activation assays, immune checkpoint assays, cytokine and growth factor detection, and more.


Our product upgrades are

  • Easier to operate

  • The signal is more stable

  • Wider application


Genomeditech, relying on its unique luciferase reporter gene system and based on the mechanism of action (MOA) of drugs, has developed a series of firefly luciferase reporter gene cell line products. These products cover most functionally active targets. When used together, this reagent can more effectively assist researchers in evaluating the in vitro biological activity of small molecules, monoclonal antibodies, bispecific antibodies, and other drugs.

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Product Center > Reporter gene detection-related reagents
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Reporter gene detection-related reagents
Reporter Gene

A reporter gene is a type of gene that makes the expression product easy to detect. Its mechanism involves fusing the coding sequence of the reporter gene and its expression regulatory sequence with the target gene to form a chimeric gene. Under the influence of the regulatory sequence, the gene is expressed. By detecting the expression product of the reporter gene, the expression status of the target gene can be evaluated.


Common reporter genes include luciferase, chloramphenicol acetyltransferase (CAT), β-galactosidase (β-gal), secreted alkaline phosphatase (SEAP), and green fluorescent protein (GFP), among others.

Firefly Luciferase

Firefly luciferase is a protein with a molecular weight of approximately 61 kDa. Under conditions where ATP, magnesium ions, and oxygen are present, it catalyzes the oxidation of luciferin to oxyluciferin. During this oxidation process, it emits bioluminescence with a wavelength of around 560 nm.


image.png


Due to its strong specificity, high sensitivity, low endogenous activity, and resistance to interference from other substances within the cell, luciferase is widely used as a reporter gene (marker protein).



Product Application

It is suitable for bioactivity detection based on reporter genes, such as Fc effector assays, T cell activation assays, immune checkpoint assays, cytokine and growth factor detection, and more.


Our product upgrades are

  • Easier to operate

  • The signal is more stable

  • Wider application


Genomeditech, relying on its unique luciferase reporter gene system and based on the mechanism of action (MOA) of drugs, has developed a series of firefly luciferase reporter gene cell line products. These products cover most functionally active targets. When used together, this reagent can more effectively assist researchers in evaluating the in vitro biological activity of small molecules, monoclonal antibodies, bispecific antibodies, and other drugs.

Message Consultation
If you have more questions, please fill in the relevant information,we'll respond as soon as possible to assist you!
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Submit
You can also contact us on the Scientist and Science Exchange marketplaces.
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