Cat.No：GM-48237AB
Product：Anti-CD200R hIgG4 Antibody(I-4P)
Cat.No：GM-48237AB
Product：Anti-CD200R hIgG4 Antibody(I-4P)
GM-48237AB-10 10 μg
GM-48237AB-100 100 μg
GM-48237AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone I-4P
Source/Isotype Monoclonal Human IgG4 /κ
Application Flow Cytometry
Specificity Detects CD200R.
Gene CD200R.
Other Names CD200R1, HCRTR2, MOX2R, OX2R
Gene ID Q8TD46-1 (Human); A0A2K5WLV7-1 (Cynomolgus)
Background CD200R is expressed on the surface of myeloid cells and CD4+ T cells. It interacts with CD200 transmembrane glycoprotein that can be expressed on variety of cells including neurons, epithelial cells, endothelial cells, fibroblasts, and lymphoid cells. This gene encodes a receptor for the CD200 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-48237AB
Product：Anti-CD200R hIgG4 Antibody(I-4P)
GM-48237AB-10 10 μg
GM-48237AB-100 100 μg
GM-48237AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone I-4P
Source/Isotype Monoclonal Human IgG4 /κ
Application Flow Cytometry
Specificity Detects CD200R.
Gene CD200R.
Other Names CD200R1, HCRTR2, MOX2R, OX2R
Gene ID Q8TD46-1 (Human); A0A2K5WLV7-1 (Cynomolgus)
Background CD200R is expressed on the surface of myeloid cells and CD4+ T cells. It interacts with CD200 transmembrane glycoprotein that can be expressed on variety of cells including neurons, epithelial cells, endothelial cells, fibroblasts, and lymphoid cells. This gene encodes a receptor for the CD200 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
