Cat. No:GM-30129AB
Product:Anti-H_TFRC(CD71) hIgG1 Antibody(Pabinafusp)
Cat. No:GM-30129AB
Product:Anti-H_TFRC(CD71) hIgG1 Antibody(Pabinafusp)
GM-30129AB-10 10 μg
GM-30129AB-100 100 μg
GM-30129AB-1000 1mg
Species Reactivity Human
Specificity Detects human CD71. It also detects cynomolgus CD71.
Source/Isotype Monoclonal human IgG1, κ
Other Names IMD46, T9, TFR, TFR1, TR, TRFR, p90
Gene ID 7037(human); 102136007(cynomolgus)
Application Flow cytometry: 0.5 μg-4 μg/test; FC-Quality tested
Background Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene. TfR1 is a transmembrane glycoprotein composed of two disulfide-linked monomers joined by two disulfide bonds. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. TfR1 has been shown to interact with GABARAP and HFE. CD71 is a robust immunohistochemistry marker for chorionic villi, especially in necrotic specimens. Among white blood cells and precursors, CD71 is expressed only by erythroid precursors within the normal hematopoietic marrow and spleen, in contrast to glycophorin that marks all types of red blood cells.
Storage Store at +4℃ short term (1-2 weeks). Store at -20℃ long term
Formulation Phosphate-buffered solution, pH 7.2.
Cat. No:GM-30129AB
Product:Anti-H_TFRC(CD71) hIgG1 Antibody(Pabinafusp)
GM-30129AB-10 10 μg
GM-30129AB-100 100 μg
GM-30129AB-1000 1mg
Species Reactivity Human
Specificity Detects human CD71. It also detects cynomolgus CD71.
Source/Isotype Monoclonal human IgG1, κ
Other Names IMD46, T9, TFR, TFR1, TR, TRFR, p90
Gene ID 7037(human); 102136007(cynomolgus)
Application Flow cytometry: 0.5 μg-4 μg/test; FC-Quality tested
Background Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene. TfR1 is a transmembrane glycoprotein composed of two disulfide-linked monomers joined by two disulfide bonds. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. TfR1 has been shown to interact with GABARAP and HFE. CD71 is a robust immunohistochemistry marker for chorionic villi, especially in necrotic specimens. Among white blood cells and precursors, CD71 is expressed only by erythroid precursors within the normal hematopoietic marrow and spleen, in contrast to glycophorin that marks all types of red blood cells.
Storage Store at +4℃ short term (1-2 weeks). Store at -20℃ long term
Formulation Phosphate-buffered solution, pH 7.2.