Cat.No：GM-50887AB
Product：Anti-H_TNFRSF10B(DR5) hIgG1 Antibody(Conatumumab)
Cat.No：GM-50887AB
Product：Anti-H_TNFRSF10B(DR5) hIgG1 Antibody(Conatumumab)
GM-50887AB-10 10 μg
GM-50887AB-100 100 μg
GM-50887AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Conatumumab
Source/Isotype Monoclonal human IgG1, κ
Application Flow Cytometry
Specificity Detects TNFRSF10B.
Gene TNFRSF10B(DR5)
Other Names CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Gene ID 8795(human), 102133727(cynomolgus)
Background The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L) and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Cat.No：GM-50887AB
Product：Anti-H_TNFRSF10B(DR5) hIgG1 Antibody(Conatumumab)
GM-50887AB-10 10 μg
GM-50887AB-100 100 μg
GM-50887AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Conatumumab
Source/Isotype Monoclonal human IgG1, κ
Application Flow Cytometry
Specificity Detects TNFRSF10B.
Gene TNFRSF10B(DR5)
Other Names CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Gene ID 8795(human), 102133727(cynomolgus)
Background The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L) and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
