Cat.No：GM-81147AB
Product：Anti-Trop2-SN38 ADC(Dar8)[Sacituzumab govitecan]
Cat.No：GM-81147AB
Product：Anti-Trop2-SN38 ADC(Dar8)[Sacituzumab govitecan]
GM-81147AB-100 100μg
GM-81147AB-1mg 1mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity >95% as determined by SDS-PAGE
Drug-to-Antibody Ratio (DAR) 8.0
Endotoxin <1 EU/mg, determined by LAL gel clotting assay
Sterility 0.22 μm Filtered
Target TROP2
Clone Sacituzumab govitecan
Alternative Names IMMU-132; hRS7-SN-38; hRS7-SN-38-ADC; hRS7-[CL-SN-38]; hrS7-SN-38
Source/Isotype Monoclonal Human IgG1(REEM),Kappa
Application Positive control of Cytotoxicity Assay
Description Sacituzumab govitecan is a conjugate of the humanized anti-Trop-2 monoclonal antibody linked with SN-38, the active metabolite of irinotecan. Each antibody having on average 7.6 molecules of SN-38 attached. Linkage to an antibody allows the drug to specifically target cells expressing Trop-2.
Formulation 20 mM Histidine, pH 6.0
Storage temp. Store at +4°C short term. Store at -80°C for 36 months, avoiding freeze/thaw cycles.
Cat.No：GM-81147AB
Product：Anti-Trop2-SN38 ADC(Dar8)[Sacituzumab govitecan]
GM-81147AB-100 100μg
GM-81147AB-1mg 1mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity >95% as determined by SDS-PAGE
Drug-to-Antibody Ratio (DAR) 8.0
Endotoxin <1 EU/mg, determined by LAL gel clotting assay
Sterility 0.22 μm Filtered
Target TROP2
Clone Sacituzumab govitecan
Alternative Names IMMU-132; hRS7-SN-38; hRS7-SN-38-ADC; hRS7-[CL-SN-38]; hrS7-SN-38
Source/Isotype Monoclonal Human IgG1(REEM),Kappa
Application Positive control of Cytotoxicity Assay
Description Sacituzumab govitecan is a conjugate of the humanized anti-Trop-2 monoclonal antibody linked with SN-38, the active metabolite of irinotecan. Each antibody having on average 7.6 molecules of SN-38 attached. Linkage to an antibody allows the drug to specifically target cells expressing Trop-2.
Formulation 20 mM Histidine, pH 6.0
Storage temp. Store at +4°C short term. Store at -80°C for 36 months, avoiding freeze/thaw cycles.
