Cat.No:GM-81145AB
Product:Anti-HER2-DXD ADC(Dar8)[Trastuzumab Deruxtecan]
Cat.No:GM-81145AB
Product:Anti-HER2-DXD ADC(Dar8)[Trastuzumab Deruxtecan]
GM-81145AB-100 100μg
GM-81145AB-1mg 1mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity >95% as determined by SDS-PAGE
Drug-to-Antibody Ratio (DAR) 8.0
Endotoxin <1 EU/mg, determined by LAL gel clotting assay
Sterility 0.22 μm Filtered
Target HER2
Clone Trastuzumab Deruxtecan
Alternative Names DS-8201; DS-8201a
Source / Isotype Monoclonal Human IgG1 (KEEM),Kappa
Application Positive control of Cytotoxicity Assay
Description Trastuzumab deruxtecan (DS-8201) is an antibody-drug conjugate composed or ADC of an anti-HER2 (human epidermal growth factor receptor 2) antibody, a cleavable tetrapeptide-based linker, and a cytotoxic topoisomerase I inhibitor.
Formulation 20 mM Histidine, pH 6.0
Storage temp. Store at +4°C short term. Store at -80°C for 36 months, avoiding freeze/thaw cycles.
Cat.No:GM-81145AB
Product:Anti-HER2-DXD ADC(Dar8)[Trastuzumab Deruxtecan]
GM-81145AB-100 100μg
GM-81145AB-1mg 1mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity >95% as determined by SDS-PAGE
Drug-to-Antibody Ratio (DAR) 8.0
Endotoxin <1 EU/mg, determined by LAL gel clotting assay
Sterility 0.22 μm Filtered
Target HER2
Clone Trastuzumab Deruxtecan
Alternative Names DS-8201; DS-8201a
Source / Isotype Monoclonal Human IgG1 (KEEM),Kappa
Application Positive control of Cytotoxicity Assay
Description Trastuzumab deruxtecan (DS-8201) is an antibody-drug conjugate composed or ADC of an anti-HER2 (human epidermal growth factor receptor 2) antibody, a cleavable tetrapeptide-based linker, and a cytotoxic topoisomerase I inhibitor.
Formulation 20 mM Histidine, pH 6.0
Storage temp. Store at +4°C short term. Store at -80°C for 36 months, avoiding freeze/thaw cycles.