OX40 is a cell membrane protein also known as CD134. It is an important costimulatory molecule that is mainly expressed on activated T cells and NK cells. OX40 signaling pathway in regulating immune response plays an important role in the process. When OX40 binds to its ligands, it activates multiple signaling pathways that promote T-cell proliferation, survival, and function. This signaling pathway is critical for regulating the activity of immune cells and the maintenance of immune responses. The OX40 signaling pathway is also considered to have potential applications in immunotherapy and immune regulation.