Cat. No：GM-046001RP
Product：Recombinant DT3C Protein
Cat. No：GM-046001RP
Product：Recombinant DT3C Protein
GM-046001RP-1：100 μg
GM-046001RP-2：1 mg
GM-046001RP Recombinant DT3C protein from Genomeditech is expressed in Escherichia coli (E. coli), comprising 33-417aa (P00588) & 291-497aa (P19909), with an 8´His tag sequence placed at the N-terminus of the DT3C coding sequence. The purity is ≥90% (SDS-PAGE), with a molecular weight of 69.4 kDa. It is dissolved in PBS at pH7.4, sterile filtered through a 0.2 μm membrane, and endotoxin levels are < 1 EU/μg.
The GM-046001RP recombinant DT3C protein is straightforward to use, forming mAb-DT3C conjugates within 30 minutes of antibody incubation. This conjugate can be directly added to cultured cells in full medium for incubation. Its in vitro functionality resembles antibody-drug conjugates (ADCs), delivering the cytotoxic effects of diphtheria toxin specifically to target cells through internalization, assessing the efficiency of mAb internalization by cells.
Cat. No：GM-046001RP
Product：Recombinant DT3C Protein
GM-046001RP-1：100 μg
GM-046001RP-2：1 mg
GM-046001RP Recombinant DT3C protein from Genomeditech is expressed in Escherichia coli (E. coli), comprising 33-417aa (P00588) & 291-497aa (P19909), with an 8´His tag sequence placed at the N-terminus of the DT3C coding sequence. The purity is ≥90% (SDS-PAGE), with a molecular weight of 69.4 kDa. It is dissolved in PBS at pH7.4, sterile filtered through a 0.2 μm membrane, and endotoxin levels are < 1 EU/μg.
The GM-046001RP recombinant DT3C protein is straightforward to use, forming mAb-DT3C conjugates within 30 minutes of antibody incubation. This conjugate can be directly added to cultured cells in full medium for incubation. Its in vitro functionality resembles antibody-drug conjugates (ADCs), delivering the cytotoxic effects of diphtheria toxin specifically to target cells through internalization, assessing the efficiency of mAb internalization by cells.
