Cat. No：GM-30132AB
Product：Anti-CD46 hIgG1 Antibody(YS5FL)
Cat. No：GM-30132AB
Product：Anti-CD46 hIgG1 Antibody(YS5FL)
GM-30132AB-10 10 μg
GM-30132AB-100 100 μg
GM-30132AB-1000 1 mg
Species Reactivity Human
Clone YS5FL
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry
Specificity Detects CD46
Gene CD46
Other Names AHUS2, MCP, MIC10, TLX, TRA2.10
Gene ID 4179 (human); 102146832 (Cynomolgus)
Background The CD46 gene plays a critical role in complement regulation, immune evasion, and metabolic regulation. Its mutations or abnormal expression are closely associated with various diseases, such as atypical hemolytic uremic syndrome (aHUS), autoimmune diseases, and cancer. Antibodies targeting CD46 (e.g., TRA2.10) have broad applications in basic research and clinical studies, including detecting protein expression, investigating complement regulatory mechanisms, and exploring cancer immunotherapy strategies. Additionally, CD46 may be indirectly linked to molecules such as MIC10 and TLX through metabolic or signaling pathways, providing new directions for future research.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-30132AB
Product：Anti-CD46 hIgG1 Antibody(YS5FL)
GM-30132AB-10 10 μg
GM-30132AB-100 100 μg
GM-30132AB-1000 1 mg
Species Reactivity Human
Clone YS5FL
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry
Specificity Detects CD46
Gene CD46
Other Names AHUS2, MCP, MIC10, TLX, TRA2.10
Gene ID 4179 (human); 102146832 (Cynomolgus)
Background The CD46 gene plays a critical role in complement regulation, immune evasion, and metabolic regulation. Its mutations or abnormal expression are closely associated with various diseases, such as atypical hemolytic uremic syndrome (aHUS), autoimmune diseases, and cancer. Antibodies targeting CD46 (e.g., TRA2.10) have broad applications in basic research and clinical studies, including detecting protein expression, investigating complement regulatory mechanisms, and exploring cancer immunotherapy strategies. Additionally, CD46 may be indirectly linked to molecules such as MIC10 and TLX through metabolic or signaling pathways, providing new directions for future research.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
