Cat.No：GM-31018AB
Product：Anti-H_TSLPR hIgG1 Antibody
Cat.No：GM-31018AB
Product：Anti-H_TSLPR hIgG1 Antibody
GM-31018AB-10 10 μg
GM-31018AB-100 100 μg
GM-31018AB-1000 1 mg
Species Reactivity Human
Source/Isotype Monoclonal human IgG1 /κ
Application Flow Cytometry；Block assay
Specificity Detects TSLPR
Gene TSLPR
Other Names CRL2Y, CRLF2
Gene ID Q9HC73-1 (human)
Background TSLPR encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-31018AB
Product：Anti-H_TSLPR hIgG1 Antibody
GM-31018AB-10 10 μg
GM-31018AB-100 100 μg
GM-31018AB-1000 1 mg
Species Reactivity Human
Source/Isotype Monoclonal human IgG1 /κ
Application Flow Cytometry；Block assay
Specificity Detects TSLPR
Gene TSLPR
Other Names CRL2Y, CRLF2
Gene ID Q9HC73-1 (human)
Background TSLPR encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
