Cat. No：GM-50874AB
Product ：Anti-OSMR hIgG4 Antibody(Vixarelimab)
Cat. No：GM-50874AB
Product ：Anti-OSMR hIgG4 Antibody(Vixarelimab)
GM-50874AB-10 10 μg
GM-50874AB-100 100 μg
GM-50874AB-1000 1mg
Species Reactivity | Human |
Clone | Vixarelimab |
Source/Isotype | Monoclonal human hIgG4, λ |
Application | Flow cytometry; |
Other Names | OSMRB; PLCA1; IL-31RB; OSMRbeta; IL-31R-beta |
Gene ID | 9180 (human) |
Background | Interleukin-31 (IL-31) is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens.IL-31 signals via a receptor complex that is composed of IL-31 receptor A (IL31RA) and oncostatin M receptor (OSMR) subunits. These receptor subunits are expressed in activated monocytes and in unstimulated epithelial cells. IL-31RA binds IL-31 through its cytokine binding domain (CBD). |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
Cat. No：GM-50874AB
Product ：Anti-OSMR hIgG4 Antibody(Vixarelimab)
GM-50874AB-10 10 μg
GM-50874AB-100 100 μg
GM-50874AB-1000 1mg
Species Reactivity | Human |
Clone | Vixarelimab |
Source/Isotype | Monoclonal human hIgG4, λ |
Application | Flow cytometry; |
Other Names | OSMRB; PLCA1; IL-31RB; OSMRbeta; IL-31R-beta |
Gene ID | 9180 (human) |
Background | Interleukin-31 (IL-31) is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens.IL-31 signals via a receptor complex that is composed of IL-31 receptor A (IL31RA) and oncostatin M receptor (OSMR) subunits. These receptor subunits are expressed in activated monocytes and in unstimulated epithelial cells. IL-31RA binds IL-31 through its cytokine binding domain (CBD). |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
