Cat.No：GM-87841AB
Product：Anti-MUSK mIgG2a Antibody(3B2g2m1)
Cat.No：GM-87841AB
Product：Anti-MUSK mIgG2a Antibody(3B2g2m1)
GM-87841AB-10 10 μg
GM-87841AB-100 100 μg
GM-87841AB-1000 1 mg
Species Reactivity Mouse, human, Cynomolgus
Clone 3B2g2m1
Source/Isotype Monoclonal mIgG2a, κ
Application Bioactivity-ELISA
Specificity Detects MUSK
Gene MUSK
Other Names CMS9, FADS, FADS1
Gene ID 18198 (Mouse); 4593 (human); 102127677 (Cynomolgus);
Background This gene encodes a member of the protein tyrosine kinase family. The encoded protein is a type 1 receptor-like protein located in muscle membrane that is activated by the heparan sulfate proteoglycan agrin released by nerve cells. The encoded protein activates signaling cascades responsible for multiple aspects of motor neuron and muscle development, including organization of the postsynaptic membrane, synaptic gene transcription, patterning of skeletal muscle, anchoring of acetylcholinesterase, and guidance of motor axons.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-87841AB
Product：Anti-MUSK mIgG2a Antibody(3B2g2m1)
GM-87841AB-10 10 μg
GM-87841AB-100 100 μg
GM-87841AB-1000 1 mg
Species Reactivity Mouse, human, Cynomolgus
Clone 3B2g2m1
Source/Isotype Monoclonal mIgG2a, κ
Application Bioactivity-ELISA
Specificity Detects MUSK
Gene MUSK
Other Names CMS9, FADS, FADS1
Gene ID 18198 (Mouse); 4593 (human); 102127677 (Cynomolgus);
Background This gene encodes a member of the protein tyrosine kinase family. The encoded protein is a type 1 receptor-like protein located in muscle membrane that is activated by the heparan sulfate proteoglycan agrin released by nerve cells. The encoded protein activates signaling cascades responsible for multiple aspects of motor neuron and muscle development, including organization of the postsynaptic membrane, synaptic gene transcription, patterning of skeletal muscle, anchoring of acetylcholinesterase, and guidance of motor axons.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
