Cat. No：GM-87952AB
Product：Anti-PD1 hlgG1 Antibody(Rosnilimab)
Cat. No：GM-87952AB
Product：Anti-PD1 hlgG1 Antibody(Rosnilimab)
GM-87952AB-10 10 μg
GM-87952AB-100 100 μg
GM-87952AB-1000 1 mg
Species Reactivity | Human |
Clone | Rosnilimab |
Source/Isotype | Monoclonal human IgG1/κ |
Application | Assay |
Specificity | Detects PD1 |
Gene | PD1 |
Other Names | CD279, PD-1, PDCD1, SLEB2, hPD-1, hPD-l, hSLE1 |
Gene ID | 5133 (human) |
Background | Programmed cell death protein-1 (PD-1) is an inhibitory immune checkpoint primarily expressed by immune cells. In the tumor microenvironment, PD-1 binds to its ligands PD-L1 and PD-L2, inhibiting T cell activation and proliferation, which allows tumor cells to evade immune system surveillance. As a novel agonist, Rosnilimab offers a new approach for T cell immune activation and may open new avenues for the treatment of tumors and autoimmune diseases. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
Cat. No：GM-87952AB
Product：Anti-PD1 hlgG1 Antibody(Rosnilimab)
GM-87952AB-10 10 μg
GM-87952AB-100 100 μg
GM-87952AB-1000 1 mg
Species Reactivity | Human |
Clone | Rosnilimab |
Source/Isotype | Monoclonal human IgG1/κ |
Application | Assay |
Specificity | Detects PD1 |
Gene | PD1 |
Other Names | CD279, PD-1, PDCD1, SLEB2, hPD-1, hPD-l, hSLE1 |
Gene ID | 5133 (human) |
Background | Programmed cell death protein-1 (PD-1) is an inhibitory immune checkpoint primarily expressed by immune cells. In the tumor microenvironment, PD-1 binds to its ligands PD-L1 and PD-L2, inhibiting T cell activation and proliferation, which allows tumor cells to evade immune system surveillance. As a novel agonist, Rosnilimab offers a new approach for T cell immune activation and may open new avenues for the treatment of tumors and autoimmune diseases. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
