Cat. No：GM-88109AB
Product：Anti-VEGFR-1 hIgG1 Antibody (Icrucumab)
Cat. No：GM-88109AB
Product：Anti-VEGFR-1 hIgG1 Antibody (Icrucumab)
GM-88109AB-10 10 μg
GM-88109AB-100 100 μg
GM-88109AB-1000 1mg
Species Reactivity | Human |
Clone | Icrucumab |
Source/Isotype | Human IgG1,K214R/D356E/L358M, Kappa |
Application | Flow Cytometry |
Target | Detects VEGFR-1 |
Gene | VEGFR-1 |
Other Names | VEGFR1 |
Gene ID | 9606 (Human) |
Background | Vegfr-1(Vascular Endothelial Growth Factor Receptor 1) encodes a Receptor tyrosine kinase that belongs to the VEGFR family and is involved in angiogenesis and Vascular permeability regulation. The main ligands of this gene are VEGF-A, VEGF-B, PLGF (placental growth factor) , etc. . After binding, it activates its intracellular kinase activity, recruits and activates downstream signaling pathways (such as PI3K-AKT, RAS-ERK, PLC γ, SRC, etc.) , promote Endothelium proliferation, migration, survival and lumen formation. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
Cat. No：GM-88109AB
Product：Anti-VEGFR-1 hIgG1 Antibody (Icrucumab)
GM-88109AB-10 10 μg
GM-88109AB-100 100 μg
GM-88109AB-1000 1mg
Species Reactivity | Human |
Clone | Icrucumab |
Source/Isotype | Human IgG1,K214R/D356E/L358M, Kappa |
Application | Flow Cytometry |
Target | Detects VEGFR-1 |
Gene | VEGFR-1 |
Other Names | VEGFR1 |
Gene ID | 9606 (Human) |
Background | Vegfr-1(Vascular Endothelial Growth Factor Receptor 1) encodes a Receptor tyrosine kinase that belongs to the VEGFR family and is involved in angiogenesis and Vascular permeability regulation. The main ligands of this gene are VEGF-A, VEGF-B, PLGF (placental growth factor) , etc. . After binding, it activates its intracellular kinase activity, recruits and activates downstream signaling pathways (such as PI3K-AKT, RAS-ERK, PLC γ, SRC, etc.) , promote Endothelium proliferation, migration, survival and lumen formation. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
