Cat. No：GM-88159AB
Product：Anti-FcεRI hIgG1 Antibody (1E7)
Cat. No：GM-88159AB
Product：Anti-FcεRI hIgG1 Antibody (1E7)
GM-88159AB-10 10 μg
GM-88159AB-100 100 μg
GM-88159AB-1000 1mg
Species Reactivity | Human |
Clone | 1E7 |
Source/Isotype | Monoclonal Human IgG1 κ |
Application | Bioactivity-ELISA |
Target | Detects FcεRI |
Gene | FcεRI |
Other Names | FCE1A, FCERIA, FcERI |
Gene ID | 2205 (Human) |
Background | FcεRI (high-affinity IgE receptor) is expressed on the surfaces of mast cells, eosinophils, platelets, and other immune cells, and serves as a key receptor in classical allergic reactions. The receptor is conventionally composed of α, β, and γ subunits, with the α subunit responsible for high-affinity IgE binding, and the β/γ subunits participating in signal transduction. Expression is predominantly observed in mast cells and mast cell–like cells, basophils, and a subset of dendritic cells, among others. Transcriptional regulation of FcεRI involves multiple transcription factors, including the GATA family, PU.1, and C/EBP, as well as epigenetic factors. Environmental stimuli such as infections, inflammatory cues, and certain IgE-related stimuli can modulate the expression levels of FcεRI subunits. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
Cat. No：GM-88159AB
Product：Anti-FcεRI hIgG1 Antibody (1E7)
GM-88159AB-10 10 μg
GM-88159AB-100 100 μg
GM-88159AB-1000 1mg
Species Reactivity | Human |
Clone | 1E7 |
Source/Isotype | Monoclonal Human IgG1 κ |
Application | Bioactivity-ELISA |
Target | Detects FcεRI |
Gene | FcεRI |
Other Names | FCE1A, FCERIA, FcERI |
Gene ID | 2205 (Human) |
Background | FcεRI (high-affinity IgE receptor) is expressed on the surfaces of mast cells, eosinophils, platelets, and other immune cells, and serves as a key receptor in classical allergic reactions. The receptor is conventionally composed of α, β, and γ subunits, with the α subunit responsible for high-affinity IgE binding, and the β/γ subunits participating in signal transduction. Expression is predominantly observed in mast cells and mast cell–like cells, basophils, and a subset of dendritic cells, among others. Transcriptional regulation of FcεRI involves multiple transcription factors, including the GATA family, PU.1, and C/EBP, as well as epigenetic factors. Environmental stimuli such as infections, inflammatory cues, and certain IgE-related stimuli can modulate the expression levels of FcεRI subunits. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
