|
Species Reactivity |
Human |
|
Clone |
Ab17 |
|
Source/Isotype |
Human IgG1 (L234A/L235A), Kappa |
|
Application |
Flow Cytometry |
|
Target |
Detects LPAR1 |
|
Gene |
LPAR1 |
|
Other Names |
EDG2, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1 |
|
Gene ID |
1902 (human) |
|
Background |
The lysophosphatidic acid receptor 1 encoded by the LPAR1 gene is an important member of the G protein-coupled receptor family, which mainly mediates LPA signaling, and plays an important role in the regulation of LPA signaling, plays a central role in regulating key physiological processes such as cell proliferation, migration, and survival. It is involved in various pathological processes such as cancer, pulmonary fibrosis, radiation-induced lung injury and neurodevelopmental disorders, and is an important target for drug research and development. |
|
Storage |
Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
|
Formulation |
Supplied as a 0.2 μm filtered solution of PBS, pH 7.2-7.4. |
|
Endotoxin |
< 1 EU/mg, determined by LAL gel clotting assay
|