|
Species Reactivity |
Human |
|
Clone |
SA338a |
|
Source/Isotype |
Human IgG1, Kappa |
|
Application |
Bioactivity-ELISA |
|
Target |
Detects IL18BP |
|
Gene |
IL18BP |
|
Other Names |
FVHa |
|
Gene ID |
10068 (Human) |
|
Background |
IL-18 binding protein encoded by IL-18BP gene is a member of immunoglobulin superfamily, which is located on human chromosome 11q13 and has tissue-specific expression pattern, especially in spleen. By producing IL-18BPA, IL-18BPB and other subtypes of proteins, the gene specifically binds to IL-18 cytokines and inhibits their induced IFN-γ production and T cell activation, thus, it plays a key role in negatively regulating the immune response. |
|
Storage |
Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
|
Formulation |
Supplied as a 0.2 μm filtered solution of PBS, pH 7.2-7.4. |
|
Endotoxin |
< 1 EU/mg, determined by LAL gel clotting assay
|
