Species Reactivity Human
Clone QX007N
Source/Isotype Human IgG1 (KDEL),Kappa
Application /
Specificity Detects IL33
Gene IL33
Other Names IL1RL1,DER4,FIT-1,IL33R,ST2,ST2L,ST2V,T1
Gene ID 90865 (human)
Background Interleukin 33 (IL-33) is a protein that in humans is encoded by the IL33 gene. Interleukin 33 is a member of the IL-1 family that potently drives production of T helper-2 (Th2)-associated cytokines. IL-33 is expressed by a wide variety of cell types, including fibroblasts, mast cells, dendritic cells, macrophages, osteoblasts, endothelial cells, and epithelial cells.IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay