| Species Reactivity | Human |
| Clone | samrotamab |
| Source/Isotype | Human IgG1(KEEM), Kappa |
| Application | / |
| Specificity | Detects LRRC15 |
| Gene | LRRC15 |
| Other Names | LIB |
| Gene ID | 131578 (human) |
| Background | Samrotamab is a humanized IgG1-κ chimeric antibody that targets LRRC15, and its research background is closely linked to innovative explorations in the field of oncology therapy. LRRC15 is a type I transmembrane protein involved in cell-to-cell and cell-to-matrix interactions, and it has been shown to be involved in a variety of cellular processes, it is highly expressed on the surface of a variety of solid tumors (such as breast cancer, lung cancer, ovarian cancer) and tumor-associated fibroblasts (CAFS) , but rarely expressed in normal cells. This“Tumor specificity” makes LRRC15 a promising new anti-cancer target. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
| Species Reactivity | Human |
| Clone | samrotamab |
| Source/Isotype | Human IgG1(KEEM), Kappa |
| Application | / |
| Specificity | Detects LRRC15 |
| Gene | LRRC15 |
| Other Names | LIB |
| Gene ID | 131578 (human) |
| Background | Samrotamab is a humanized IgG1-κ chimeric antibody that targets LRRC15, and its research background is closely linked to innovative explorations in the field of oncology therapy. LRRC15 is a type I transmembrane protein involved in cell-to-cell and cell-to-matrix interactions, and it has been shown to be involved in a variety of cellular processes, it is highly expressed on the surface of a variety of solid tumors (such as breast cancer, lung cancer, ovarian cancer) and tumor-associated fibroblasts (CAFS) , but rarely expressed in normal cells. This“Tumor specificity” makes LRRC15 a promising new anti-cancer target. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
