Genomeditech(Shanghai) Co.LTD

Lentivirus

Cell Line Development

Protein Expression

Plasmid DNA Preparation Services

Adeno-associated Virus

Cell-based Assay

Antibody Services

Reporter Gene Detection Services

Plasmid

Cell lines

Cytokines Immune checkpoints GPCR CLDN TAA Kinase TLR NK Antibody function Immunotherapy target In vivo imaging TNF LILR WNT Others Reference cells

Molecular Reference Standards

Reporter gene detection-related reagents

Lentivirus

Proteins

Cytokines TAA Immune checkpoints Immunotherapy target GPCR TNF Kinase Others

Pseudovirus control material

Reagents related to cell function detection and analysis

Adeno-Associated Virus (AAV)

Antibodies

In Vivo MAb Antibodies Anti-payload antibodies Loading Controls Antibodies & Tag Antibodies Biosimilar Antibodies

Pseudovirus

Genoagent (Brand name of reagents)

News

Insights

Lentivirus

过表达慢病毒干扰慢病毒

Cell Line Development

过表达细胞系构建服务敲低细胞系构建服务敲除细胞系构建服务报告基因细胞株构建服务 Luciferase标记细胞株

Protein Expression

Plasmid DNA Preparation Services

过表达质粒构建干扰质粒构建突变/截短质粒构建荧光素酶报告基因质粒构建

Adeno-associated Virus

过表达AAV 干扰AAV

Cell-based Assay

抗体Binding检测蛋白/抗体药物功能检测 ADCC/P 活性检测 ADC药物CTG杀伤检测 CCK8细胞增值检测克隆形成细胞迁移/侵袭细胞周期/凋亡划痕实验

Antibody Services

Reporter Gene Detection Services

miRNA与靶基因调控研究转录因子调控/promoter活性研究

Current position：Technical Service > Plasmid DNA Preparation Services > 干扰质粒构建 > 案例展示

案例展示

服务简介

根据客户研究的目的基因设计shRNA，并将其克隆到相应的载体，转染细胞即可实现抑制基因表达的目的，与化学合成的siRNA相比，质粒性质更稳定，且对基因的抑制持续时间更长。

案例展示

客户文章节选

IF=16.6009,Nature communications，上海交通大学药学院,干扰质粒；shRNA.

Cullin5 drives experimental asthma exacerbations by modulating alveolar macrophage antiviral immunity

IF=12.657，Journal of Experimental & Clinical Cancer Research，上海交通大学医学院，干扰质粒

CYT997 (Lexibulin) induces apoptosis and autophagy through the activation of mutually reinforced ER stress and ROS in osteosarcoma

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