| Alternative Names | BTN3A3,BTF3 |
| Source | Human BTN3A3 Protein; His Tag (GM-88578RP) is expressed from human 293 cells (HEK-293). It contains AA Gln 30 - Trp 248 (Accession # AAH15815). This protein carries a his tag at the C-terminus. |
| Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 1 EU/μg, determined by LAL gel clotting assay |
| Predicted Mol Mass | 24.4 KDa |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Description | BTN3A3 (butyrophilin subfamily 3 member A3) is a type I transmembrane glycoprotein of the immunoglobulin superfamily that is implicated in the regulation of T cell and NK cell responses. The BTN3 family members are expressed on the cell surface and modulate immune activation and proliferation, making BTN3A3 a useful target for studying immune checkpoint–like pathways and tumor-immune interactions. Recombinant BTN3A3 protein can be used for antibody screening, ligand-receptor interaction assays, and functional studies in immuno-oncology and inflammation. |
| Alternative Names | BTN3A3,BTF3 |
| Source | Human BTN3A3 Protein; His Tag (GM-88578RP) is expressed from human 293 cells (HEK-293). It contains AA Gln 30 - Trp 248 (Accession # AAH15815). This protein carries a his tag at the C-terminus. |
| Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 1 EU/μg, determined by LAL gel clotting assay |
| Predicted Mol Mass | 24.4 KDa |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Description | BTN3A3 (butyrophilin subfamily 3 member A3) is a type I transmembrane glycoprotein of the immunoglobulin superfamily that is implicated in the regulation of T cell and NK cell responses. The BTN3 family members are expressed on the cell surface and modulate immune activation and proliferation, making BTN3A3 a useful target for studying immune checkpoint–like pathways and tumor-immune interactions. Recombinant BTN3A3 protein can be used for antibody screening, ligand-receptor interaction assays, and functional studies in immuno-oncology and inflammation. |
